Nutritional Support Strategies for Refeeding Syndrome in ICU Patients: A Review of Current Evidence

This study employed an evidence-based approach to synthesize and integrate relevant evidence regarding early nutritional support for patients with ICU refeeding syndrome, identifying clinically applicable nutritional support strategies to provide a reference for early nutritional management in such patients.

Based on the "6S" pyramid evidence hierarchy model, systematic searches were conducted in core domestic and international databases for guidelines, expert consensus documents, high-quality randomized controlled trials (RCTs), systematic reviews, and evidence summaries related to early nutritional support for ICU refeeding syndrome patients, with the search period spanning from database establishment to December 25,2025.

A total of 16 publications were included, comprising 3 guidelines, 2 clinical decision-making documents, 4 systematic reviews, 2 cohort studies, 1 RCT, and 4 expert consensus documents. The evidence was systematically organized into 24 key evidence-based recommendations covering five aspects: multidisciplinary team collaboration, timing of nutritional assessment, indications for initiating and terminating nutritional support, specific nutritional interventions, and health education.

The evidence framework developed in this study provides a standardized reference for early nutritional management of ICU refeeding syndrome patients, addressing the lack of unified clinical guidelines and holding significant implications for reducing complication risks and improving patient outcomes.