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Updated: Jun 30, 2026

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
Shoulder contouring with botulinum toxin and fillers
Kyu-Ho Yi1, Isabella Rosellini2, Kang Hoon Choi3
1You and I Clinic, Seoul, Republic of Korea.
Background:
Interest in shoulder aesthetics has increased, with emphasis on clavicular definition and balanced shoulder contour. Minimally invasive approaches combining hyaluronic acid fillers and botulinum toxin type A (BoNT-A, Letibo, Hugel, Korea) have been proposed to address both structural and muscular components.
Methods:
This technical note describes three patients who underwent combined acromial and clavicular filler injections with BoNT-A administered to the upper trapezius and deltoid regions for shoulder contour refinement. Filler volume was individualized according to baseline shoulder slope, clavicular/acromial projection deficiency, soft-tissue thickness, and the degree of asymmetry, with total volumes of 10, 12, and 15 cc. BoNT-A was administered as 25 units distributed across five anatomically defined injection points. Outcomes were assessed by standardized clinical photography, clinical follow-up, patient-reported satisfaction, and adverse-event grading using the Common Terminology Criteria for Adverse Events framework.
Results:
All three patients demonstrated visible, qualitative improvement in shoulder contour, including enhanced clavicular definition and reduced trapezius prominence. Patient-reported satisfaction was favorable in all cases. No major complications were observed. Minor adverse events, including transient swelling and discomfort, were classified as mild CTCAE grade 1 events and resolved without intervention.
Conclusions:
This three-case technical note illustrates a feasible anatomy-guided multimodal approach for shoulder contour refinement. Because of the very small sample size, lack of a control group, and predominantly qualitative outcome assessment, these observations should not be interpreted as evidence of efficacy, safety, or generalizability. Larger controlled studies with standardized morphometric measurements, validated patient-reported outcome instruments, and longer follow-up are required.
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