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Updated: Jul 1, 2026

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
Published on: June 11, 2015
Characterization of genomic diversity in bacteriophages infecting Rhodococcus
Dominic R Garza1, Daria L Di Blasi1, Karen K Klyczek2
1Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, California, United States of America.
Abstract:
Bacteriophages are ubiquitous and highly genetically diverse biological entities. Here we describe the isolation and bioinformatic characterization of 56 phages isolated on two Rhodococcus spp. They include both lytic and temperate phages and are grouped with previously described Rhodococcus phages into six clusters and 16 singletons based on genome similarity. Their genome sizes range from 43.9 kbp to 142 kbp and they have a G + C content ranging from 41.2% to 68.4%. Some of the Rhodococcus phages are more closely related to phages isolated on non-Rhodococcus Actinobacteria hosts than they are to phages isolated from the same host genus, demonstrating complex evolutionary histories. This study further expands the growing field of Actinobacteriophage genomics.
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