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Therapy for Stage IV Non-Small Cell Lung Cancer With Driver Alterations: ASCO Living Guideline, Version 2026.3.2
Sonam Puri1, Nofisat Ismaila2, Ibrahim Hanna Azar3
1Moffitt Cancer Center, Tampa, FL, US.
Summary
Living guidelines provide regular updates for rapidly evolving clinical practice based on continuous evidence reviews. These guidelines support, but do not replace, clinician judgment for patient care.
Area of Science:
- Oncology
- Clinical Practice Guidelines
Background:
- Rapidly evolving evidence necessitates frequent updates in clinical practice.
- Living guidelines address the need for dynamic recommendations in healthcare.
Purpose of the Study:
- To describe the methodology and framework of ASCO Living Guidelines.
- To outline the process for systematic literature review and guideline updates.
Main Methods:
- Guidelines are developed for rapidly changing evidence areas.
- A standing expert panel conducts continuous systematic reviews of health literature.
- Updates are published regularly on the ASCO Publications website.
Main Results:
- ASCO Living Guidelines are updated on a regular schedule.
- The process adheres to the ASCO Guidelines Methodology Manual and Conflict of Interest Policy.
Conclusions:
- Living guidelines offer a dynamic approach to clinical recommendations.
- These guidelines are intended to aid, not supersede, clinical decision-making.
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