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Updated: Jul 1, 2026
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Synthesis and Characterization of Supramolecular Colloids
Published on: April 22, 2016
Photophysical Properties of Coumarin 343 and Structural Changes in Reline-Pluronic Systems With Varying Block
Sapana Sinha1, Sagar Srivastava1, Vinod K Aswal2
1Department of Chemistry, Indian Institute of Technology Patna, Patna, Bihar, India.
Chemistry, an Asian Journal
|June 29, 2026
Summary
Reline, a deep eutectic solvent, alters Pluronic micelle properties. This study reveals how reline affects Pluronic assemblies, impacting their potential for advanced biomedical applications.
Area of Science:
- Physical Chemistry
- Materials Science
- Nanotechnology
Background:
- Water's role as HBD/HBA in reline (Type III DES) is documented.
- Pluronic block copolymers form self-assembled micelles.
- Understanding ternary component effects on micellar systems is crucial for applications.
Purpose of the Study:
- Investigate reline's effect as a ternary component on Pluronic (P123, F108) assemblies.
- Utilize coumarin 343 (C343-) as a fluorescent probe.
- Characterize structural and dynamic changes in Pluronic micelles upon reline addition.
Main Methods:
- Spectroscopic techniques (UV-Vis absorption, steady-state and time-resolved fluorescence).
- Differential scanning calorimetry (DSC).
- Fourier transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), and small-angle neutron scattering (SANS).
Main Results:
- Reline addition decreased the critical micelle temperature of Pluronics.
- Spectroscopic data indicated C343- localization within the micelles.
- Changes in fluorescence anisotropy decay times varied between P123 and F108 systems.
- FTIR, DLS, and SANS confirmed alterations in micellar structure.
Conclusions:
- Reline significantly influences Pluronic micelle formation and properties.
- The findings provide insights into designing hybrid nanocarriers.
- This research supports the development of advanced biomedical applications using Pluronic-reline systems.
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