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Clinical Outcomes and Predictors of Adverse Events in Influenza Patients Managed in a Hospital-at-Home Program: A
Emmanuel Coloma-Bazán1,2, Anna Aldea1,2, Ainoa Ugarte1,2
1Hospital at Home Unit, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Background:
Hospital-at-home (HaH) is increasingly used to manage acute conditions like influenza, but data on long-term outcomes remain limited.
Objective:
To identify clinical predictors of 30- and 90-day adverse outcomes among influenza patients treated at HaH.
Methods:
We retrospectively analyzed 270 adult patients with laboratory-confirmed influenza managed at HaH over 10 influenza seasons. Outcomes included emergency room (ER) visits, hospital readmissions, and all-cause mortality at 30 and 90 days.
Results:
At 30 days, 12.4% had ED visits, 5.1% were readmitted, and 3.4% died; at 90 days, these increased to 16.2%, 6.5%, and 6.8%, respectively. Multivariable analysis identified reduced glomerular filtration rate (GFR < 60 mL/min/1.73 m²) at discharge and early ER visits as independent predictors of poor outcomes.
Conclusions:
Renal impairment and early postdischarge ER use are significant predictors of adverse outcomes in influenza patients managed through HaH. These findings help clinicians optimize risk stratification and follow-up strategies during seasonal influenza peaks.
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