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Published on: August 2, 2011
Regional epidemiology of fowl adenovirus in China from 1988 to 2024: A meta-analysis
Mengke Si1, Yiwei Wang1, Junxue Qiu1
1Anhui Province Key Laboratory of Animal Nutritional Regulation and Health, Anhui Science and Technology University, Feng yang, China.
Background:
Fowl adenovirus (FAdV) induces hydropericardium hepatitis syndrome and inclusion body hepatitis in fowl, causing substantial economic losses to China's fowl industry. However, nationwide epidemiological data on FAdV remain fragmented.
Aim:
This meta-analysis aimed to estimate the pooled prevalence of FAdV in Chinese fowl from 1988 to 2024.
Methods:
In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, 58 cross-sectional studies from databases (PubMed, China National Knowledge Infrastructure, etc.) were included. Pooled prevalence and subgroup analyses were performed using a random-effects model with Stata 12.0.
Results:
The overall FAdV prevalence was 37% (95% CI: 32.00%-42.00%) with high heterogeneity (I²>97%). Central China had the highest prevalence (50%), and Southwest China had the lowest (28%). Winter (20%) and adult/rearing stages (both 33%) showed higher prevalence; geese had the lowest species rate (12%).
Conclusion:
FAdV is highly prevalent in Chinese fowl with notable, fowl species, detection method, sample type, seasonal, and developmental stage. Targeted surveillance, detection method, sample type, developmental stage, seasonal biosecurity, and standardized diagnostics are essential for FAdV control.
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