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Artificial Intelligence in Gynecologic Oncology: Current Applications, Clinical Challenges, and Future Perspectives
Dimitrios Alefragkis1,2, George Mpourazanis3, Pietro Serra4,5
1Second Department of Critical Care, Attikon University General Hospital, Athens, GRC.
Cureus
|June 30, 2026
Summary
Artificial intelligence (AI) shows promise in diagnosing gynecologic cancers like cervical, endometrial, and ovarian cancers. Further research is needed to address challenges for widespread clinical adoption.
Area of Science:
- Gynecologic Oncology
- Medical Artificial Intelligence
- Digital Pathology
Background:
- Gynecologic cancers (cervical, endometrial, ovarian, etc.) significantly impact global women's health.
- Current treatments show variable results, and diagnosis remains a challenge.
Purpose of the Study:
- To explore the application of artificial intelligence (AI) in the diagnosis and prognostication of gynecologic cancers.
- To assess the potential of multi-platform methods combining clinical and imaging data for personalized therapies.
Main Methods:
- AI has been utilized for risk prognostication in endometrial and ovarian cancers using digital pathology.
- Automated Pap smear analysis for cervical cancer detection has been developed.
- Multi-platform approaches integrating clinical and imaging data are being explored.
Main Results:
- AI demonstrates potential in risk stratification and automated diagnostics for specific gynecologic cancers.
- Combining clinical data with imaging shows promise for prognostic assessment and personalized treatment strategies.
Conclusions:
- AI offers a promising avenue for improving the diagnosis and management of gynecologic cancers.
- Addressing challenges such as data heterogeneity, ethical concerns, and algorithmic bias is crucial for clinical integration and validation.
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