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Updated: Jul 1, 2026

A "Patient-Like" Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis
Published on: October 24, 2015
Hepatocellular carcinoma muscle and skin metastasis: A case-report
Mahyar Daskareh1,2, Reihaneh Mortazavi Ardestani3, Ali Nosrati Andevari4
1Department of Radiology, Ziaeian Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Abstract:
A 55-year-old patient with chronic hepatitis B infection who developed hepatocellular carcinoma. The tumor was managed with primary therapeutic resection. On postoperative follow-up imaging, rising alpha-fetoprotein noted which led into contrast-enhanced MRI of abdomen. On Imaging review, an abdominal wall lesion suspected, which was more conspicuous on the post contrast images. There are several differential diagnosis for these soft tissue lesions which demonstrate many shared imaging characteristics. Musculoskeletal and cutaneous metastases from hepatocellular carcinoma are uncommon, though clinically critical since it changes management. We strongly recommend detailed evaluation of skin and musculoskeletal regions among these patients.
