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Updated: Jul 1, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Characteristics, predictors, and management of post-extubation dysphagia in critically Ill children: a scoping review
Yaokang Xue1,2, Baorong Zhang1, Xiaoshuang Zhao3
1Department of Pediatric Intensive Care Unit, The First Hospital of Jilin University, Changchun, China.
Insights
Post-extubation dysphagia (PED) in children is common, with high incidence and identified risk factors. However, diagnostic and management approaches lack standardization and validation.
Area of Science:
- Pediatric critical care medicine
- Swallowing disorders
- Evidence synthesis
Background:
- Post-extubation dysphagia (PED) is a frequent complication in critically ill children.
- It is linked to aspiration, malnutrition, and extended hospital stays.
- Current pediatric PED assessment and management lack standardized pathways and show significant variability.
Purpose of the Study:
- To conduct a scoping review of pediatric PED evidence.
- To map incidence, clinical characteristics, and predictors.
- To evaluate prediction tools, screening instruments, and management strategies.
Main Methods:
- Systematic search of nine databases (PubMed, Embase, etc.) with a March 2026 cutoff.
- Inclusion of 15 studies (cohort, RCT, quasi-experimental, scale-development).
- Narrative synthesis following the JBI scoping review methodology.
Main Results:
- Studies published 2018-2026, predominantly from China and Brazil.
- Reported PED incidence between 28.36% and 68.94%.
- No bedside instruments validated against VFSS/FEES; CRISPED score shows internal validation (C-statistic 0.85-0.86).
- Key predictors: intubation duration, age, IWS (Tier 1); neurological comorbidities, ≥2 intubations (Tier 2); delirium (Tier 3).
- Interventions focused on oral motor training without standardized protocols.
Conclusions:
- Pediatric PED is prevalent with consistent risk factors but lacks standardized diagnostic criteria, assessment tools, and interventions.
- A critical gap is the lack of instrumental validation for bedside assessment tools.
- Future research needs multicenter studies for unified criteria, validated screening tools, and a multidisciplinary management framework.
Background:
Post-extubation dysphagia (PED) is a common complication in critically ill children, associated with aspiration, malnutrition, and prolonged hospitalization. Standardized pediatric-specific assessment and management pathways are lacking, and published studies show substantial heterogeneity in diagnostic criteria, assessment timing, and intervention strategies.
Objective:
This scoping review maps available evidence on pediatric PED, addressing: (1) incidence and clinical characteristics; (2) categories and effect sizes of independent predictors; and (3) the current state of prediction tools, bedside screening instruments, and management strategies.
Methods:
Nine databases were searched systematically-PubMed, Embase, Cochrane Library, Web of Science, CINAHL, CNKI, Wanfang, VIP, and CBM-with a search cutoff of 12 March 2026. Fifteen studies were included, encompassing cohort studies, randomized controlled trials, quasi-experimental studies, and scale-development studies. Data were synthesized narratively following the JBI scoping review methodological framework.
Results:
Included studies were published between 2018 and 2026; 73.3% (11/15) appeared after 2022, originating primarily from mainland China (n = 10) and Brazil (n = 3). The clinical apparent incidence ranged from 28.36% to 68.94%. No included bedside assessment instrument was validated against VFSS or FEES,representing a central methodological gap in the current evidence base.Independent predictors were categorized into three evidence tiers: Tier 1: intubation duration, age, and IWS; Tier 2: neurological comorbidities and number of intubations ≥2; Tier 3:delirium.The CRISPED score is the only prediction tool with temporal internal validation (C-statistic 0.85-0.86). No assessment instrument has been validated against an instrumental gold standard. Interventions centered on oral motor training, with no standardization in frequency, intensity, or multidisciplinary integration.
Conclusion:
Pediatric PED incidence is high and core risk factors have been repeatedly reported across multiple multivariable models, but the field shows substantial heterogeneity in diagnostic definitions, assessment tools, and intervention protocols. The absence of instrumental validation for bedside assessment tools is the central limitation. Key gaps include the absence of gold-standard diagnostic accuracy studies, externally validated prediction models, and standardized intervention pathways. Future research should prioritize multicenter prospective studies to unify diagnostic criteria, develop age-appropriate bedside screening tools, and establish a nurse-led multidisciplinary management framework.
Systematic Review Registration:
Open Science Framework (OSF), identifier doi: 10.17605/OSF.IO/XSJ9B.
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