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Two-Year Follow-Up of the MINI WELL Non-Diffractive Extended Depth-of-Focus Intraocular Lens: A Retrospective

Alessandra Sborgia^1,2, Maria Cristina Curatolo³, Dionisio Franco Barattini⁴

¹Eye Clinic Dept, Hospital "SS. Annunziata" ASL Taranto, Taranto, Italy.

Clinical Ophthalmology (Auckland, N.Z.)

|June 30, 2026

Summary

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The MINI WELL non-diffractive extended depth-of-focus (EDoF) intraocular lens provides stable visual outcomes and functional vision two years after cataract surgery. This EDoF lens demonstrates a favorable safety profile, supporting its long-term efficacy.

Area of Science:

Ophthalmology
Biomedical Engineering
Optometry

Background:

Cataract surgery is a common procedure to restore vision.
Extended depth-of-focus (EDOF) intraocular lenses (IOLs) aim to provide a continuous range of vision.
Assessing the long-term performance of EDOF IOLs is crucial for patient satisfaction and visual function.

Purpose of the Study:

To evaluate the long-term visual outcomes, functional vision, and safety of the MINI WELL non-diffractive EDOF IOL.
To analyze data over a two-year follow-up period after implantation.
To assess the stability of visual performance with this specific EDOF IOL technology.

Main Methods:

A monocentric, retrospective, observational study was conducted.
Included patients received binocular implantation of the MINI WELL non-diffractive EDOF IOL.

Keywords:

cataract defocus curve extended depth-of-focus intraocular lens presbyopia safety visual performance

Related Experiment Videos

Evaluated visual acuity (distance, intermediate, near), defocus curves, contrast sensitivity, reading performance, and patient-reported outcomes over 24 months.

Main Results:

All 23 patients maintained binocular visual acuity at all distances at 24 months.
Binocular uncorrected distance visual acuity of 20/32 or better was achieved by all patients.
The MINI WELL EDOF IOL demonstrated functional near and intermediate vision, fluent reading, and a favorable safety profile with minimal adverse events.

Conclusions:

The MINI WELL non-diffractive EDOF IOL provides sustained visual outcomes and functional vision up to two years post-implantation.
The lens exhibits a favorable safety profile, indicating its long-term stability and efficacy.
Further prospective and comparative studies are recommended to validate these findings.