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Related Concept Videos

Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Gallbladder01:17

Gallbladder

The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins the common...
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:

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Related Experiment Video

Updated: Jul 1, 2026

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
07:44

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

EUS-Guided Gallbladder Drainage in Acute Cholecystitis With Contained Perforation: An International Multicenter

Marco Spadaccini1,2, Gianluca Franchellucci1, Francesco Auriemma3

  • 1Endoscopy Unit, IRCCS Humanitas Research Hospital, Milan, Italy.

Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society
|June 30, 2026
PubMed
Summary

Endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) is feasible and safe for treating acute cholecystitis with contained gallbladder perforation in high-risk patients. This minimally invasive approach offers a viable alternative when surgery is not an option.

Keywords:
EUS‐GBDacute cholecystitisgallbladder perforation

Related Experiment Videos

Last Updated: Jul 1, 2026

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
07:44

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

Area of Science:

  • Gastroenterology
  • Interventional Endoscopy
  • Surgical Innovation

Background:

  • Acute cholecystitis (AC) in poor surgical candidates often requires alternative management.
  • Endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) is an option for AC, but its use in contained gallbladder perforation (CGP) is less understood.
  • Percutaneous drainage is often preferred for AC with CGP due to perceived safety concerns with EUS-GBD.

Purpose of the Study:

  • To evaluate the feasibility and safety of EUS-GBD using Lumen-apposing metal stents (LAMS) for AC complicated by CGP.
  • To assess adverse events and clinical success rates associated with EUS-GBD in this specific patient population.

Main Methods:

  • Retrospective, international, multicenter study involving 57 patients across 10 tertiary centers.
  • Primary outcome: safety assessed by adverse events (AE) using AGREE classification.
  • Secondary outcomes: clinical success defined by symptom resolution and objective improvement within 3 days.

Main Results:

  • Adverse events occurred in 12.3% of patients (n=7), with varying severity.
  • The only intra-procedural AE was LAMS misdeployment, managed endoscopically.
  • Clinical success was high (96%), with significant resolution of peri-cholecystic collections (94.4%).

Conclusions:

  • EUS-GBD with LAMS is a feasible and safe treatment option for AC with CGP in patients unsuitable for surgery.
  • This approach provides a valuable minimally invasive alternative to traditional methods.