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Related Concept Videos

Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which leads...
Myasthenia Gravis ll: Pathophysiology01:22

Myasthenia Gravis ll: Pathophysiology

The disease process of myasthenia gravis begins at the neuromuscular junction, where antibodies attack key proteins needed for muscle activation. This immune reaction weakens signal transmission, leading to the characteristic muscle fatigue and weakness that define the condition.Immune-Mediated DamageIn most individuals, antibodies target acetylcholine receptors (AChRs) on the postsynaptic membrane of muscle cells. By blocking acetylcholine binding, these antibodies prevent the nerve signal...
Myasthenia Gravis: Diagnostic Tests01:15

Myasthenia Gravis: Diagnostic Tests

Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Chemical Synapses01:26

Chemical Synapses

Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
Chemical Synapses01:26

Chemical Synapses

Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...

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Related Experiment Video

Updated: Jul 1, 2026

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy
05:06

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy

Published on: July 14, 2023

Mindfulness for Myasthenia Gravis.

Sui H Wong1

  • 1Consultant Neurologist and Neuro-Ophthalmologist, Moorfields Eye Hospital NHSFT, Guys and St Thomas' Hospitals NHSFT, Kings College London, London, UK.

Muscle & Nerve
|June 30, 2026
PubMed
Summary
This summary is machine-generated.

Mindfulness-based interventions may benefit myasthenia gravis (MG) patients by improving fatigue and mood. Further research is needed to explore MBIs

Keywords:
mindfulnessmyasthenia gravisquality of lifewell‐being

Related Experiment Videos

Last Updated: Jul 1, 2026

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy
05:06

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy

Published on: July 14, 2023

Area of Science:

  • Integrative medicine and immunology.
  • Neuromuscular disorders and psychological well-being.

Background:

  • Mindfulness-based interventions (MBIs) show promise for chronic and autoimmune conditions.
  • MBIs impact immunological pathways, improving fatigue, mood, and quality of life.
  • Myasthenia gravis (MG) is an autoimmune disorder with limited research on MBIs.

Purpose of the Study:

  • To explore the potential benefits of MBIs for individuals with myasthenia gravis.
  • To investigate the underlying mechanisms of MBIs in the context of MG.
  • To provide recommendations for designing and implementing MBIs tailored to MG patients.

Main Methods:

  • Literature review on MBIs in chronic and autoimmune diseases.
  • Analysis of existing research on psychological and biological effects of MBIs.
  • Case-based suggestions for adapting mindfulness practices for MG.

Main Results:

  • MBIs have demonstrated positive effects on immunological pathways and patient-reported outcomes in other chronic conditions.
  • The mechanisms by which MBIs could benefit MG patients warrant further investigation.
  • Special considerations are necessary when adapting MBIs for the unique needs of individuals with MG.

Conclusions:

  • MBIs present a potential avenue for improving the quality of life for individuals with myasthenia gravis.
  • Future research should focus on the efficacy and mechanisms of MBIs specifically in the MG population.
  • Tailored mindfulness practices may offer adjunctive support for managing MG symptoms and improving overall well-being.