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Adenoviral pneumonia with organising features in an immunocompetent patient: When steroids make the difference

V Shrinath1, Ramakant Singh1, Anoop Kumar Nair2

  • 1Department of Medicine, INHS Asvini, Mumbai, Maharashtra, India.

Lung India : Official Organ of Indian Chest Society
|June 30, 2026
PubMed

Insights

Adenovirus pneumonia is rare in immunocompetent adults. This case report highlights an excellent response to corticosteroid therapy in a patient with severe adenovirus pneumonia and hypoxemic respiratory failure.

Area of Science:

  • Medicine
  • Infectious Diseases
  • Pulmonology

Background:

  • Community-acquired pneumonia (CAP) is a leading cause of mortality and morbidity.
  • Adenovirus is a frequent cause of lower respiratory tract infections (LRTI) in children but rarely causes pneumonia in immunocompetent adults.
  • Limited medical literature and standardized therapies exist for adult adenovirus pneumonia.

Purpose of the Study:

  • To report a case of adenovirus pneumonia in an immunocompetent adult.
  • To evaluate the efficacy of ribavirin and corticosteroids in managing severe adenovirus pneumonia.
  • To highlight corticosteroids as a potential therapeutic option for severe adenovirus pneumonia.

Main Methods:

  • A case report of a 35-year-old immunocompetent woman with adenovirus pneumonia and hypoxemic respiratory failure.
  • Management included ribavirin and corticosteroids.
  • Clinical response to therapy was monitored.

Main Results:

  • The patient experienced hypoxemic respiratory failure due to adenovirus pneumonia.
  • She showed an excellent response to corticosteroid therapy.
  • Ribavirin was also administered, but the response to corticosteroids was particularly notable.

Conclusions:

  • Adenovirus pneumonia can occur in immunocompetent adults, presenting with severe respiratory compromise.
  • Corticosteroids may be a valuable therapeutic tool for managing severe cases of adenovirus pneumonia.
  • Further research is warranted to establish standardized treatment protocols for this rare condition.
Keywords:
Key Words: Adenoviruscorticosteroidshypoxemic respiratory failureribavirinviral pneumonia

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