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Related Concept Videos

Microbes in Beverage Production01:25

Microbes in Beverage Production

Alcoholic beverages such as wine, beer, and spirits are the products of microbial fermentation processes that transform simple sugars into ethanol and a wide array of complex flavor compounds. These transformations rely on the metabolic activities of specific yeasts and bacteria, which are selected and controlled to yield the desired beverage characteristics.Wine Fermentation and MaturationWine production begins with the crushing of grapes to release juice and pulp, forming a must that is...
Microbes in Food Production01:29

Microbes in Food Production

Microbial fermentation is central to food biotechnology, enhancing flavor, texture, preservation, and stability. Fermentative microorganisms metabolize carbohydrates into organic acids, alcohols, and other metabolites that inhibit spoilage organisms and improve digestibility while contributing distinctive sensory qualities.In baking, amylases naturally present in flour hydrolyze starch into monosaccharides such as glucose, which Saccharomyces cerevisiae ferments anaerobically. Through...
Microbial Fermentation01:23

Microbial Fermentation

Fermentation is a crucial anaerobic metabolic process that enables microbes to derive energy from sugar without relying on oxygen or an electron transport chain. This process is fundamental to various biological and industrial applications and is classified based on the metabolic products generated.Role of Pyruvate in FermentationPyruvate and its derivatives serve as key electron acceptors in fermentative pathways. The oxidation of NADH to regenerate NAD+ is essential for the continuation of...
Fungal Phylum Ascomycota01:28

Fungal Phylum Ascomycota

Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
Microbiota of the Stomach and Small Intestine01:27

Microbiota of the Stomach and Small Intestine

The human gastrointestinal (GI) tract is characterized by distinct physicochemical conditions that shape its microbial communities. Among these, the stomach presents a particularly challenging environment for microbial colonization due to its highly acidic pH, ranging from 1 to 3. This extreme acidity effectively limits microbial density. However, certain acid-tolerant microorganisms are capable of surviving in this niche. Notably, Helicobacter pylori can colonize the gastric mucosa,...
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Fungal Group Zygomycota

Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...

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Updated: Jul 1, 2026

Transformation of Probiotic Yeast and Their Recovery from Gastrointestinal Immune Tissues Following Oral Gavage in Mice
12:12

Transformation of Probiotic Yeast and Their Recovery from Gastrointestinal Immune Tissues Following Oral Gavage in Mice

Published on: February 8, 2016

Yeasts in the Gastrointestinal Tract.

Katherine D Mueller1, Soo Chan Lee1

  • 1Department of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX, USA.

FEMS Yeast Research
|June 30, 2026
PubMed
Summary
This summary is machine-generated.

Fungi, particularly yeasts, play a significant role in human gut health and immunity. This review explores their associations with inflammatory bowel diseases, potential in cancer therapy, and therapeutic applications.

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Last Updated: Jul 1, 2026

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Area of Science:

  • Microbiology
  • Immunology
  • Gastroenterology

Background:

  • The human gastrointestinal (GI) microbiota modulates host health.
  • Interest in gut fungi, especially yeasts, has historically lagged behind bacteria.
  • Fungi are prevalent in the GI tract and significantly impact host immunity.

Purpose of the Study:

  • To examine the associations between yeasts and human health outcomes.
  • To review the role of yeasts in inflammatory bowel diseases (IBD).
  • To explore the potential of yeasts in cancer therapy and as therapeutic agents.

Main Methods:

  • Literature review of existing studies on gut fungi and human health.
  • Analysis of associations between specific yeasts and IBD.
  • Evaluation of current research on fungal biomarkers for cancer therapy.
  • Exploration of the therapeutic potential of yeasts.

Main Results:

  • Yeasts are associated with inflammatory bowel diseases.
  • Fungal presence may predict outcomes in cancer therapy.
  • Yeasts show potential as therapeutic effectors in the GI tract.

Conclusions:

  • Despite challenges in data analysis and understanding fungal morphology, yeasts offer promising clinical translation pathways.
  • Further research into the GI mycobiome is warranted to harness its therapeutic potential.
  • Yeasts represent a significant, yet understudied, component of the human gut.