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Related Experiment Video

Updated: Jul 1, 2026

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
03:25

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Single-Use vs Reusable Catheters for Intermittent Catheterization in Patients With Urinary Retention: The COMPARE

Felice E E van Veen1, Coen H H Christiaans1, Sophie A Berendsen1

  • 1Department of Urology, Erasmus University Medical Center, Rotterdam, the Netherlands.

JAMA Network Open
|June 30, 2026
PubMed
Summary

Reusable catheters are as safe as single-use catheters for preventing urinary tract infections (UTIs) in clean intermittent catheterization (CIC). Patient preference and comfort varied, indicating a need for improved reusable catheter design.

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Published on: January 30, 2018

Area of Science:

  • Urology
  • Infectious Disease Management
  • Medical Device Technology

Background:

  • Clean intermittent catheterization (CIC) is standard for urinary retention.
  • Single-use catheters pose environmental and financial burdens.
  • Limited data exists on the safety and efficacy of reusable catheters for CIC.

Purpose of the Study:

  • To determine if reusable catheters are noninferior to single-use catheters in preventing urinary tract infections (UTIs) during CIC.
  • To compare catheter-related complications, adverse events, and patient-reported outcomes between reusable and single-use catheters.

Main Methods:

  • A multicenter, noninferiority randomized clinical trial involving 386 patients aged 16+ performing CIC.
  • Participants were randomized to use either reusable catheters (disinfected with sodium hypochlorite) or single-use catheters.
  • The primary outcome was UTI incidence per patient-month, with a 1-year follow-up.

Main Results:

  • Reusable catheters were noninferior to single-use catheters regarding UTI incidence (0.050 vs 0.054 UTIs/patient-month).
  • Catheter-related complications and serious adverse events were similar between groups.
  • Urethral irritation was more frequent with reusable catheters, while quality of life and satisfaction varied between groups.

Conclusions:

  • Reusable catheters offer a viable alternative to single-use catheters for CIC, demonstrating noninferiority in UTI prevention.
  • Patient tolerability and reported outcomes suggest a need for design improvements in reusable catheters.
  • Individual patient preferences and comfort are crucial for the successful implementation of reusable catheter systems.