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Updated: Jul 2, 2026

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example
Published on: October 24, 2012
Impact of Aging on Attentional Networks in Cortical Coding of Auditory Space
Kavassery Venkateswaran Nisha1, Suprabha S Kappadi2, Ajith Kumar Uppunda1
1Department of Audiology, All India Institute of Speech and Hearing Center of Hearing Sciences, Manasagangothri, Mysore.
Background:
The current study aimed to characterize aging-related cortical changes in spatial hearing using electroencephalographic (EEG) recordings evoked in response to spatial deviants (virtual acoustic stimuli).
Methods:
A group comparison design was used in the present study. A 3-stimulus oddball paradigm containing 2 deviant stimuli and 1 standard was used to obtain P300 recordings from 64 scalp electrodes. The offline processed EEG data for spatial deviants were compared across age groups using global field power (GFP) and topographic pattern analyses. P300 was recorded on 3 groups of normal hearing listeners: 10 young adults (31-40 years), 12 middle-aged adults (41-50 years), and 13 elderly adults (51-65 years).
Results:
Group differences were evident on GFP, with the elderly adults manifesting larger GFP at the N1 and P3 regions. Further pattern analyses marked the extinction and emergence of new scalp topographies in the elderly and middle-aged groups starting from 130 ms and lasting until 800 ms.
Conclusion:
The study provides support for aging-related deterioration in inhibitory control over neural coding of space, which becomes apparent from 130 ms poststimulus presentation.
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