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Vestibular Test Results in Patients with Common Variable Immunodeficiency
Tuğba Yılmaz1, Fakih Cihat Eravcı2, Malik Afifoğlu2
1Department of Audiology, Gülhane University of Health Sciences, Ankara, Türkiye.
Individuals with common variable immunodeficiency (CVID) show impaired vestibular function, affecting balance and eye movements. This suggests inner ear involvement in CVID patients, potentially causing dizziness and hearing loss.
Area of Science:
- Otolaryngology
- Immunology
- Neurology
Background:
- Common variable immunodeficiency (CVID) is associated with inner ear dysfunction.
- Audiological testing reveals inner ear abnormalities in CVID patients.
Purpose of the Study:
- To investigate vestibular system function in individuals with CVID.
- To assess balance and eye movement control in CVID patients.
Main Methods:
- Caloric testing, video head impulse test (vHIT), and computerized dynamic posturography (CDP) were performed.
- 24 CVID patients and 22 healthy controls participated.
Main Results:
- CVID patients exhibited significantly lower caloric test values compared to controls.
- Computerized dynamic posturography revealed poorer sensory organization in CVID patients.
- Video head impulse test showed reduced vestibulo-ocular reflex gains in CVID patients.
Conclusions:
- Vestibular dysfunction is evident in individuals with CVID.
- CVID patients may experience dizziness and hearing loss, even at diagnosis.
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