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Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Tonsillitis II: Management01:26

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
Streptococcal Pharyngitis01:27

Streptococcal Pharyngitis

Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Acute Pharyngitis01:30

Acute Pharyngitis

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Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...

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Related Experiment Video

Updated: Jul 2, 2026

A Standardized Acupotomy Protocol For The Treatment of Tenosynovitis of Hand Flexor Tendons In Human Patients
07:05

A Standardized Acupotomy Protocol For The Treatment of Tenosynovitis of Hand Flexor Tendons In Human Patients

Published on: May 26, 2026

Simplified Oral Antibiotic Regimen for Pyogenic Flexor Tenosynovitis.

Ewen Lataste1, Jérôme Jeudy2, Bruno Cesari2

  • 1Centre Hospitalier Universitaire d'Angers - 4 rue Larrey, 49000 Angers, France.

Hand Surgery & Rehabilitation
|June 30, 2026
PubMed
Summary

Minimally invasive surgery with a short oral antibiotic course is effective for early-stage pyogenic flexor tenosynovitis, offering good functional outcomes. Advanced stages may require tailored treatment due to higher failure risks.

Keywords:
Oral antibioticsOutpatientPyogenic Flexor Tenosynovitis

Related Experiment Videos

Last Updated: Jul 2, 2026

A Standardized Acupotomy Protocol For The Treatment of Tenosynovitis of Hand Flexor Tendons In Human Patients
07:05

A Standardized Acupotomy Protocol For The Treatment of Tenosynovitis of Hand Flexor Tendons In Human Patients

Published on: May 26, 2026

Area of Science:

  • Hand surgery
  • Infectious diseases
  • Orthopedic surgery

Background:

  • Pyogenic flexor tenosynovitis is a common hand infection requiring surgical intervention.
  • Postoperative antibiotic strategies for this condition are variable.
  • This study evaluates a protocol of minimally invasive surgery and short-term oral antibiotics.

Purpose of the Study:

  • To assess the safety and efficacy of outpatient management for pyogenic flexor tenosynovitis.
  • To evaluate infection control and functional outcomes at six months post-treatment.
  • To identify predictors of treatment failure and determinants of functional outcome.

Main Methods:

  • A prospective observational cohort study of 148 patients with pyogenic flexor tenosynovitis.
  • Standardized protocol: minimally invasive surgical lavage followed by a median 8-day oral antibiotic course.
  • Primary endpoints: treatment failure and functional status (Patient-Rated Wrist Evaluation - PRWE) at six months.

Main Results:

  • 93% of patients were managed as outpatients, with a 6.8% overall failure rate.
  • Stage IIB phlegmon was independently associated with treatment failure (p=0.033).
  • At six months, 74% of reassessed patients had minimal functional impairment (PRWE ≤ 10).

Conclusions:

  • Outpatient management with minimally invasive lavage and a one-week oral antibiotic regimen is safe and effective for stage I and IIA pyogenic flexor tenosynovitis.
  • Patients with stage IIB disease face a higher risk of treatment failure and may necessitate an adapted management approach.
  • This protocol demonstrates favorable infection control and functional recovery in early-stage cases.