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Related Concept Videos

Gross Anatomy of the Liver01:17

Gross Anatomy of the Liver

The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
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Related Experiment Video

Updated: Jul 2, 2026

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach
05:30

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach

Published on: August 8, 2025

Giant Omphalocele.

Anastasia M Kahan1, Michelle J Yang2, Martha A Monson3

  • 1Division of Pediatric Surgery, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah.

Neoreviews
|June 30, 2026
PubMed
Summary
This summary is machine-generated.

Giant omphalocele (GO) is a rare abdominal wall defect requiring specialized care. This review covers prenatal diagnosis, neonatal management, surgical interventions, and long-term outcomes for GO patients.

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Last Updated: Jul 2, 2026

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach
05:30

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Published on: August 8, 2025

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy
04:41

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Published on: March 10, 2023

Area of Science:

  • Pediatric Surgery
  • Neonatology
  • Maternal-Fetal Medicine

Background:

  • Omphalocele is the second most common congenital abdominal wall defect.
  • Giant omphalocele (GO) involves herniation of abdominal viscera into a sac, often including over 50% of the liver.
  • Pathophysiology involves failed abdominal wall closure and bowel return during embryogenesis.

Purpose of the Study:

  • To review the prenatal, neonatal, and surgical management of giant omphalocele.
  • To discuss the long-term outcomes for patients diagnosed with giant omphalocele.

Main Methods:

  • Review of existing literature on giant omphalocele.
  • Synthesis of information regarding diagnostic and management strategies.
  • Analysis of long-term follow-up data.

Main Results:

  • Prenatal diagnosis is typically achieved via ultrasonography.
  • Management requires a multidisciplinary approach involving obstetrics, neonatology, and pediatric surgery.
  • Surgical intervention and intensive neonatal care are crucial.

Conclusions:

  • Giant omphalocele necessitates comprehensive, multidisciplinary care from prenatal diagnosis through long-term follow-up.
  • Effective management strategies aim to improve outcomes for affected infants.
  • Further research into pathophysiology and long-term outcomes is warranted.