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Related Concept Videos

Glomerular Filtration Rate and its Regulation01:28

Glomerular Filtration Rate and its Regulation

The Glomerular Filtration Rate (GFR) is a measure of kidney function, reflecting the volume of filtrate formed per minute in the kidneys. On average, GFR is approximately 125 mL/min in males and 105 mL/min in females. Maintaining a relatively constant GFR is essential for the kidneys to effectively regulate body fluid homeostasis and maintain extracellular stability.
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What is Glycolysis?00:56

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Cells make energy by breaking down macromolecules. Cellular respiration is the biochemical process that converts "food energy" (from the chemical bonds of macromolecules) into chemical energy in the form of adenosine triphosphate (ATP). The first step of this tightly regulated and intricate process is glycolysis. The word glycolysis originates from the Latin glyco (sugar) and lysis (breakdown). Glycolysis serves two main intracellular functions: generating ATP and generating...
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Updated: Jul 2, 2026

In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy
06:22

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Published on: July 29, 2019

Exercise as a regulator of glymphatic function.

James R Broatch1, Nicholas J Saner1, Melinda L Jackson2

  • 1Exercise Prescription Laboratory, Institute for Health and Sport (IHES), Victoria University, Footscray, Victoria, Australia.

Trends in Neurosciences
|June 30, 2026
PubMed
Summary
This summary is machine-generated.

Exercise may enhance the brain

Keywords:
Alzheimer’s diseasebrain agingglianeurodegenerationphysical activitysleep

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Related Experiment Videos

Last Updated: Jul 2, 2026

In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy
06:22

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Published on: July 29, 2019

Cannula Implantation into the Cisterna Magna of Rodents
10:13

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Published on: May 23, 2018

Investigating Glycolysis in Primary Microglia Using Extracellular Flux Assay
07:21

Investigating Glycolysis in Primary Microglia Using Extracellular Flux Assay

Published on: April 10, 2026

Area of Science:

  • Neuroscience
  • Physiology

Background:

  • The glymphatic system clears brain waste, including proteins linked to neurodegenerative diseases.
  • Exercise may offer neuroprotection by influencing this system.

Purpose of the Study:

  • To review evidence on glymphatic system function, regulation, and its link to exercise.
  • To propose exercise as a modulator of glymphatic integrity.

Main Methods:

  • Literature review of animal and human studies.
  • Synthesis of data on glymphatic system organization and regulation.
  • Analysis of exercise's physiological adaptations and their impact on the glymphatic system.

Main Results:

  • The glymphatic system's role in waste clearance is increasingly recognized.
  • Exercise shows potential to modulate glymphatic function.
  • Aging and neurodegeneration can impair glymphatic function.

Conclusions:

  • Exercise may enhance glymphatic function, contributing to brain resilience.
  • Physiological adaptations to exercise provide a framework for understanding exercise's neuroprotective effects.