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Related Experiment Video

Updated: Jul 2, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
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Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

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Absorbable Micro-Aesthetic Lifting Thread for Nasolabial Fold Correction: A Multicenter, Randomized,

Donghao Jia1, Kexin Song1, Wenyun Ting1

  • 1Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Shuaifuyuan 1#, Dongcheng District, Beijing, 100730, People's Republic of China.

Aesthetic Plastic Surgery
|June 30, 2026
PubMed
Summary

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This summary is machine-generated.

A novel absorbable micro-aesthetic lifting thread demonstrated non-inferiority for nasolabial fold correction compared to a marketed thread. It showed superior early aesthetic improvement and investigator satisfaction, with a comparable safety profile.

Area of Science:

  • Aesthetic Medicine
  • Biomaterials Science
  • Dermatology

Background:

  • Absorbable lifting threads are used for facial soft tissue support and NLF correction.
  • These threads degrade naturally within the body post-implantation.

Purpose of the Study:

  • To evaluate the efficacy and safety of a novel absorbable micro-aesthetic lifting thread.
  • To compare this novel thread against a marketed polydioxanone thread for NLF correction.

Main Methods:

  • A prospective, multicenter, randomized, evaluator-blinded, parallel-controlled study.
  • 151 subjects with moderate-to-severe NLF (grade ≥3 WSRS) were randomized.
  • Primary endpoint: 7-month WSRS response rate (≥1 grade improvement).

Main Results:

Keywords:
Absorbable barbed threadsFacial rejuvenationNasolabial foldPolydioxanoneRandomized controlled trialThread lifting

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Published on: September 27, 2024

  • The novel thread achieved a 7-month response rate of 71.6% vs. 62.7% for the control, confirming non-inferiority.
  • The novel thread showed superiority in 3-month response rates, investigator satisfaction, and barb fixation (P<0.05).
  • Both groups had comparable safety profiles with no serious adverse events.

Conclusions:

  • The novel absorbable micro-aesthetic lifting thread is effective and safe for NLF correction.
  • It demonstrates non-inferiority to a marketed comparator and offers potential advantages in early results and handling.
  • The multi-plane lifting strategy combined with the novel thread shows promise for aesthetic outcomes.