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Feasibility of Enhanced Recovery After Surgery Protocol in Gallbladder Cancer.
Nisha Rateria1, Mallika Tewari1, Vinod K Dixit2
1Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005 U.P India.
Indian Journal of Surgical Oncology
|July 1, 2026
Summary
Enhanced Recovery After Surgery (ERAS) protocol adherence in gallbladder cancer patients significantly reduced length of hospital stay and postoperative complications. High compliance with ERAS guidelines is key to improving surgical outcomes.
Area of Science:
- Surgical Oncology
- Gastroenterology
- Evidence-Based Medicine
Background:
- Enhanced Recovery After Surgery (ERAS) is a multimodal approach to minimize surgical stress and improve postoperative recovery.
- Gallbladder cancer (GBC) surgery presents unique challenges for patient recovery.
- Optimizing perioperative care is crucial for improving outcomes in GBC patients.
Purpose of the Study:
- To evaluate compliance with the ERAS protocol in patients undergoing radical cholecystectomy for gallbladder cancer.
- To assess the impact of ERAS protocol compliance on postoperative outcomes, including complications and length of hospital stay.
- To identify factors influencing ERAS compliance in GBC patients.
Main Methods:
- Retrospective analysis of 45 Gallbladder Cancer patients who underwent curative surgery between January 2021 and January 2023.
- Detailed review of adherence to specific ERAS protocol elements (e.g., NGT removal, ambulation, diet progression, catheter removal, drain management).
- Correlation analysis between ERAS compliance score and postoperative outcomes (complications, length of stay, readmissions).
Main Results:
- High compliance was observed for NGT removal (72.1%) and early discharge (71.1% by POD6).
- A compliance score >66.67% predicted the absence of postoperative complications.
- Lower compliance was associated with diabetes mellitus, additional procedures, and longer operative times.
- Significantly shorter length of hospital stay was observed in patients with good ERAS compliance (p < 0.0001).
- No 30-day postoperative mortality was recorded; 26.7% experienced complications, mostly minor and conservatively managed.
Conclusions:
- The ERAS protocol can be safely and effectively implemented in the perioperative care of Gallbladder Cancer patients.
- Adherence to ERAS guidelines is associated with reduced length of hospital stay and fewer postoperative complications.
- ERAS protocol compliance is a significant predictor of favorable surgical outcomes in GBC management.
