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Laparoscopic Versus Open Radical Nephrectomy for Renal Cell Carcinoma: A Retrospective Study
Amr Abouzid1, Mosab Shetiwy1, Mohamed Hamdy1
1Department of Surgical Oncology, Oncology Center, Mansoura University (OCMU), Mansoura, Egypt.
Indian Journal of Surgical Oncology
|July 1, 2026
Summary
Laparoscopic radical nephrectomy (LRN) offers better surgical and postoperative outcomes than open radical nephrectomy (ORN) for renal cell carcinoma. LRN leads to significantly less blood loss and improved recovery times.
Area of Science:
- Urology
- Surgical Oncology
Background:
- Laparoscopic radical nephrectomy (LRN) is increasingly preferred over open radical nephrectomy (ORN) for renal cell carcinoma.
- Assessing comparative outcomes is crucial for treatment selection.
Purpose of the Study:
- To compare surgical and postoperative outcomes of LRN versus ORN in renal cell carcinoma patients.
- To evaluate the impact of both surgical approaches on patient prognosis.
Main Methods:
- Retrospective review of 74 renal cell carcinoma patients treated between May 2008 and October 2023.
- Comparison of operative time, intraoperative blood loss, ambulation, oral intake, in-hospital stay, and tumor recurrence between LRN and ORN groups.
Main Results:
- Operative times were comparable (LRN: 166.76 min vs. ORN: 164.5 min, p=0.86).
- LRN showed significantly less intraoperative blood loss (101.47 ml vs. 270.63 ml, p<0.001).
- Surgical outcomes including ambulation, oral intake, and hospital stay were significantly better with LRN (p<0.001). Tumor recurrence rates were similar (LRN: 3 vs. ORN: 4).
Conclusions:
- LRN demonstrates superior surgical and postoperative outcomes compared to ORN for renal cell carcinoma.
- These benefits are particularly evident in experienced hands and for small-sized tumors.
