Related Experiment Video
Updated: Jul 2, 2026
08:12
Invasive Hemodynamic Monitoring of Aortic and Pulmonary Artery Hemodynamics in a Large Animal Model of ARDS
Published on: November 26, 2018
Hypoxemia after thoracic aortic aneurysm repair.
Gift Owolabi1, Yuichiro Kitada1, Jack Nickles1
1Division of Cardiac, Thoracic, and Vascular Surgery, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY.
JTCVS Open
|July 1, 2026
Summary
Early postoperative hypoxemia (POH) after aortic aneurysm repair is common and linked to higher respiratory issues. Circulatory arrest (CA) did not significantly increase moderate/severe POH risk.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Anesthesiology
Background:
- Proximal aortic aneurysm repair is a complex procedure.
- Early postoperative hypoxemia (POH) is a potential complication.
- Understanding factors influencing POH is crucial for patient outcomes.
Purpose of the Study:
- To characterize early postoperative hypoxemia (POH) following proximal aortic aneurysm repair.
- To evaluate the association between POH and patient outcomes, including respiratory morbidity and mortality.
- To determine if circulatory arrest (CA) contributes to the development of POH.
Main Methods:
- A single-center retrospective study of 790 adult patients undergoing proximal aortic aneurysm repair.
- POH defined as arterial oxygen tension/inspired oxygen fraction ratio <300 mm Hg at 6 hours.
- Inverse probability of treatment weighting used to balance baseline characteristics; regression analysis evaluated factors associated with POH, including CA exposure.
Main Results:
- POH occurred in 54.8% of patients (33.7% mild, 21.1% moderate/severe).
- Increased severity of POH was associated with higher composite respiratory morbidity (P = .030).
- POH was not associated with 7-year mortality (HR, 0.77; P = .321); CA was not associated with moderate/severe POH (OR, 0.96; P = .864).
Conclusions:
- Early POH is a frequent complication after proximal aortic aneurysm repair.
- POH is linked to increased postoperative respiratory morbidity but not long-term mortality.
- Circulatory arrest does not appear to be a significant contributor to moderate/severe POH in this cohort.
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