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Published on: August 23, 2024
CD20-Negative Primary Intestinal Diffuse Large B-cell Lymphoma With TP53 Mutation in Poorly Controlled Celiac
Chaimae Bekhakh1, Anass Haloui1, Nassira Karich1
1Pathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy of Oujda, Mohammed First University of Oujda, Oujda, MAR.
Cureus
|July 1, 2026
Summary
Celiac disease (CD) patients have a higher risk of T-cell lymphoma. This report details an exceptionally rare case of CD20-negative primary intestinal large B-cell lymphoma in a woman with poorly controlled CD.
Area of Science:
- Gastroenterology
- Oncology
- Immunology
Background:
- Celiac disease (CD) is linked to increased intestinal lymphoma risk, primarily T-cell types.
- Primary intestinal large B-cell lymphoma (IBL) in CD patients is exceedingly rare.
