Assessing the health utility values of patients with six common cancers in China using the QLU-C10D: A cross-sectional survey

This study aimed to assess health utility values derived from the quality of life utility-core 10 dimensions (QLU-C10D) among 827 Chinese patients with six common cancers and to identify key factors influencing these values. Differences in QLU-C10D utility values across sociodemographic, behavioral, and clinical subgroups were analyzed using the Kruskal-Wallis H test, and key determinants were identified using median regression models. Gastric cancer patients had the highest median utility (0.802), and breast cancer patients had the lowest (0.671). Physical functioning and pain mainly influenced utility, especially in gastric and lung cancer. Economic pressure was most strongly associated with esophageal cancer, while disease stage was most strongly associated with breast cancer. This study assessed utility values in Chinese patients using the Chinese value set, offering key data for cost-utility analyses (CUA).