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Unveiling the Uncommon: Gastrointestinal Mucormycosis Unmasked by Gastrointestinal Bleeding
Yash Kanani1, Sanjana Bhagwat1, Rutvij Tope1
1Department of Gastroenterology, Deenanath Mangeshkar Hospital, Pune, India.
Abstract:
Gastrointestinal mucormycosis is a rare but life-threatening invasive fungal infection carrying mortality rates approaching 85%. We report 3 cases of gastric mucormycosis managed at our institution. Two patients presented atypically-one with refractory seizures and another with severe respiratory distress-resulting in diagnostic delays and subsequent fatal outcomes despite antifungal therapy. A third patient, diagnosed promptly following early esophagogastroduodenoscopy and biopsy, achieved complete clinical recovery. Rapid disease progression demonstrated the aggressive nature of this condition, but early diagnosis greatly improved outcomes. These cases collectively highlight the critical importance of maintaining a high index of clinical suspicion, pursuing early endoscopic biopsy of atypical gastric ulcerations, and initiating timely antifungal therapy to optimize patient prognosis.
Insights
Gastrointestinal mucormycosis is a rare, aggressive fungal infection. Early diagnosis via endoscopy and biopsy, followed by prompt antifungal treatment, is crucial for improving patient survival rates.
Area of Science:
- Medicine
- Infectious Diseases
- Gastroenterology
Background:
- Gastrointestinal mucormycosis is a rare, life-threatening invasive fungal infection.
- Mortality rates approach 85%, underscoring the severity of this condition.
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