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Updated: Jul 2, 2026

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
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Sequence-Dependent Folding of Recognition-Encoded Melamine Oligomers

Anca-Luiza Cotîrlan1, Cecilia J Anderson1, Nia E J Eyre1

  • 1Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.

Journal of the American Chemical Society
|July 1, 2026
PubMed
Summary

Recognition-encoded melamine oligomers (REMO) fold like nucleic acids. Sequence dictates folding, with specific designs achieving high stability and cooperativity for hairpin and helical structures.

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