An Approach to Globus Sensation: Clinical Pearls for Clinicians

Area of Science:

• Otolaryngology
• Gastroenterology
• Primary Care Medicine

Background:

• Globus sensation is a frequent complaint impacting quality of life.
• Diagnosis and management lack a standardized approach.
• Multiple factors contribute, including sinonasal, esophageal, and psychological elements.

Purpose of the Study:

• To review the causes of globus sensation.
• To provide a diagnostic and management framework.
• To emphasize multidisciplinary care.

Main Methods:

• Literature review of sinonasal, esophageal, and psychological causes.
• Framework for diagnosis including nasolaryngoscopy and endoscopy.
• Guidance on empirical therapy versus further testing.

Main Results:

• Identified sinonasal (e.g., post-nasal drip) and esophageal (e.g., reflux) conditions as common causes.
• Outlined diagnostic pathways based on symptoms (sinonasal, reflux, alarm symptoms, isolated).
• Suggested empirical treatments like nasal sprays or acid suppressors.

Conclusions:

• A structured, multidisciplinary approach is crucial for managing globus sensation.
• Diagnosis involves considering sinonasal, esophageal, and psychological factors.
• Management strategies should be tailored to clinical context and patient shared decision-making.