An electrochemical sensing platform based on UiO@TATF COF/CB composites for the detection of nitrofurazone
Jia Ren1, Hao Guo1, Zeyun Yang1
1Key Laboratory of Eco-Functional Polymer Materials of the Ministry of Education, Key Lab of Bioelectrochemistry and Environmental Analysis of Gansu Province, College of Chemistry and Chemical Engineering, Northwest Normal University, Gansu International Scientific and Technological Cooperation Base of Water-Retention Chemical Functional Materials, Lanzhou, 730070, P R China.
Abstract:
Nitrofurazone, a commonly used nitrofuran antibiotic, is widely applied in antimicrobial therapy as well as in aquaculture and livestock farming. However, its residues can pose risks to human health and cause environmental pollution. Therefore, the development of a highly sensitive detection method for nitrofurazone is of great significance. In this study, a novel core-shell composite material, UiO@TATF COF, was prepared by in situ growing TATF COF on the UiO-66-NH2 surface through a Schiff-base reaction using 4,4',4″-(1,3,5-triazine-2,4,6-triyl) tris(benzaldehyde) (TFPT) and 1,3,5-tris(4-aminophenyl) benzene (TAPB) as monomers. Subsequently, by further introducing the conductive material carbon black (CB), a novel electrochemical sensor UiO@TATF COF/CB/GCE was successfully constructed. Covalently linked UiO@TATF COF achieves a robust core-shell interface and possesses a large specific surface area and abundant active functional groups. The resultant sensor system exhibits clear synergistic effects, enabling electrocatalysis and sensitive detection toward nitrofurazone in food, environmental, and ointment samples with a detection limit of 0.05 µM (S/N = 3).
