Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 3, 2026

Study Motor Skill Learning by Single-pellet Reaching Tasks in Mice
06:04

Study Motor Skill Learning by Single-pellet Reaching Tasks in Mice

Published on: March 4, 2014

Y-maze performance predicts refined motor learning in mice.

Isak Karlsson1, Thawann Malfatti1, Klas Kullander1

  • 1Genomics and Neurobiology Program, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.

Plos One
|July 1, 2026
PubMed
Summary

Mice proficient in the Y-maze task, assessing declarative memory, showed better performance in the pellet reaching task, indicating predictive value for motor learning abilities.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Differentiated Presynaptic Input to OLMɑ2 Cells Along the Hippocampal Dorsoventral Axis: Implications for Hippocampal Microcircuit Function.

Hippocampus·2025
Same author

Layer-Specific Connectivity and Functional Interference of Chrna2+ Layer 5 Martinotti Cells in the Primary Motor Cortex.

The European journal of neuroscience·2025
Same author

A flowchart for adequate controls in virus-based monosynaptic tracing experiments identified Cre-independent leakage of the TVA receptor in RΦGT mice.

BMC neuroscience·2024
Same author

Alterations of auditory sensory gating in mice with noise-induced tinnitus treated with nicotine and cannabis extract.

Journal of psychopharmacology (Oxford, England)·2023
Same author

Adult spinal Dmrt3 neurons receive direct somatosensory inputs from ipsi- and contralateral primary afferents and from brainstem motor nuclei.

The Journal of comparative neurology·2022
Same author

<i>Hop</i> Mice Display Synchronous Hindlimb Locomotion and a Ventrally Fused Lumbar Spinal Cord Caused by a Point Mutation in <i>Ttc26</i>.

eNeuro·2022

Area of Science:

  • Neuroscience
  • Behavioral Science

Background:

  • The relationship between memory and motor learning abilities is not well understood.
  • Investigating the generalization of motor learning is crucial for understanding cognitive-motor interactions.

Purpose of the Study:

  • To investigate the correlation between declarative memory performance and fine motor learning in female mice.
  • To determine if memory task performance can predict motor learning capabilities.

Main Methods:

  • Utilized behavioral tasks including the open field, novel object recognition, Y-maze, vertical pole, and pellet reaching tasks in female mice.
  • Assessed exploratory behavior, declarative memory, and fine motor learning.
  • Performed leave-one-out cross-validation prediction analysis.

More Related Videos

Monitoring Fine and Associative Motor Learning in Mice Using the Erasmus Ladder
08:51

Monitoring Fine and Associative Motor Learning in Mice Using the Erasmus Ladder

Published on: December 15, 2023

Low-stress Route Learning Using the Lashley III Maze in Mice
09:14

Low-stress Route Learning Using the Lashley III Maze in Mice

Published on: May 22, 2010

Related Experiment Videos

Last Updated: Jul 3, 2026

Study Motor Skill Learning by Single-pellet Reaching Tasks in Mice
06:04

Study Motor Skill Learning by Single-pellet Reaching Tasks in Mice

Published on: March 4, 2014

Monitoring Fine and Associative Motor Learning in Mice Using the Erasmus Ladder
08:51

Monitoring Fine and Associative Motor Learning in Mice Using the Erasmus Ladder

Published on: December 15, 2023

Low-stress Route Learning Using the Lashley III Maze in Mice
09:14

Low-stress Route Learning Using the Lashley III Maze in Mice

Published on: May 22, 2010

Main Results:

  • A positive correlation was found between Y-maze (declarative memory) performance and pellet reaching (fine motor learning) task success.
  • Y-maze performance robustly predicted pellet reaching performance in mice.
  • Higher exploration rates in the Y-maze correlated with higher success ratios in the pellet reaching task.

Conclusions:

  • Performance in the Y-maze task is a reliable predictor of fine motor learning ability, as demonstrated by the pellet reaching task.
  • These findings suggest the Y-maze can serve as a pre-screening tool for motor learning performance.
  • This research provides a basis for pre-behavioral screening in studies involving complex motor tasks in mice.