Related Experiment Video
Updated: Jul 3, 2026
Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
Published on: June 10, 2025
Peristomal Pyoderma Gangrenosum Related to Systemic Lupus Erythematosus: A Case Study
Francesco Carlo Denti1,2,3,4,5,6,7, Dorina Bancea1,2,3,4,5,6,7, Giulia Vidotto1,2,3,4,5,6,7
1Francesco Carlo Denti, RN, MScN, IRCCS San Raffaele Institute, Milan, Italy.
Background:
Peristomal pyoderma gangrenosum (PPG) is a rare complication of peristomal skin. It is difficult to manage, and there are no guidelines for treatment. This case study describes the management of a patient with PPG while taking corticosteroids and cyclosporine as chronic therapy for systemic lupus erythematosus (SLE).
Case:
Mrs. T had SLE and a colostomy and developed PPG that was unresponsive to previous treatment. She was successfully treated with a barrier film, a topical corticosteroid, and an alginate dressing.
Conclusion:
The synergistic use of a barrier film, a topical corticosteroid, and an alginate proved to be effective for the management of PPG lesions in SLE.
Related Concept Videos
01:29Staphylococcal Skin Infections
01:23Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
01:25Inflammatory Bowel Disease III: Crohn's Disease