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Updated: Jul 3, 2026

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An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
Published on: December 5, 2025
Beyond Body Mass Index: Using Abdominal Wall Thickness to Guide Patient Selection for Deep Inferior Epigastric
Joyce Xiaoran Cui1, Eric Zeng1, Mary Lee Duet2
1Wake Forest University School of Medicine, United States.
Journal of Reconstructive Microsurgery
|July 1, 2026
Summary
Abdominal wall thickness (AWT) is a better predictor of DIEP flap complications than BMI alone. Measuring AWT can improve patient selection for autologous breast reconstruction.
Area of Science:
- Plastic Surgery
- Surgical Oncology
- Biomedical Engineering
Background:
- Current Body Mass Index (BMI) guidelines for autologous breast reconstruction may not accurately assess patient risk.
- Obesity and associated complications are significant concerns in DIEP flap procedures.
- Novel methods are needed to better evaluate patient suitability for DIEP flap reconstruction.
Purpose of the Study:
- To evaluate the relationship between abdominal wall thickness (AWT) and post-operative complication rates in DIEP flap reconstruction.
- To determine if AWT is a more accurate predictor of complications than BMI.
- To identify a potential AWT threshold for predicting complications.
Main Methods:
- Retrospective review of 793 patients (1310 flaps) undergoing DIEP flap reconstruction.
- Measurement of subcutaneous AWT from pre-operative CT angiograms at standardized landmarks.
- Stratification of patients by BMI and AWT categories for comparative analysis.
Main Results:
- BMI and AWT were both strong predictors of post-operative complications (p < 0.001).
- Increased AWT correlated with higher rates of wound dehiscence, infection, and fat necrosis.
- An AWT threshold of 26.3 mm was identified for predicting overall complications.
- AWT and BMI models showed comparable predictive accuracy, with AWT offering unique insights in cases of BMI/AWT mismatch.
Conclusions:
- Abdominal wall thickness (AWT) is a valuable adjunct to BMI in assessing DIEP flap eligibility.
- AWT measurement can help identify patients at higher risk of complications, especially when BMI is discordant.
- This accessible measurement method can refine patient selection for autologous breast reconstruction.

