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Congenital cytomegalovirus: Screening strategies and diagnostic challenges
Karen Ravin1, Terri Stillwell2
1Nemours Children's Hospital, Sidney Kimmel Medical College of Thomas Jefferson University, DE, USA.
Abstract:
Congenital cytomegalovirus (cCMV) infection is the most common congenital infection worldwide and a leading cause of sensorineural hearing loss (SNHL). Most newborns with cCMV will be asymptomatic at birth; however, a subset will go on to develop disease, including SNHL and neurodevelopmental problems, later in life. Given this, advocacy for newborn cCMV screening is growing. Targeted versus universal screening remains a hotly debated topic. This review will assess current diagnostic and screening modalities and explore unanswered questions.
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