Related Experiment Video
Updated: Jul 3, 2026

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction
Published on: July 18, 2025
Two Cases of Bilateral Ureteral Metastases From Prostate Cancer Initially Presenting With Postrenal Acute Kidney
Hiroshi Ushida1,2, Ryo Ikari2, Hiromu Tokuchi1
1Department of Urology Gakkentoshi Hospital Seika-cho, Kyoto Japan.
Introduction:
Although prostate-specific antigen (PSA) screening has facilitated early detection of prostate cancer, approximately 5% of patients still present with distant metastases at diagnosis. Ureteral metastasis from prostate cancer is extremely rare.
Case Presentation:
We report two cases of clinically diagnosed bilateral ureteral metastases in which postrenal acute kidney injury caused by bilateral hydronephrosis preceded the diagnosis of prostate cancer. Histopathological confirmation by ureteroscopic biopsy was not possible in either case. However, marked improvement in ureteral obstruction following initiation of androgen deprivation therapy supported the diagnosis.
Conclusion:
Bilateral ureteral metastases from prostate cancer may present with acute kidney injury, and therapeutic response to androgen deprivation therapy may provide an important diagnostic clue when pathological confirmation is difficult.
More Related Videos
06:39Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma
Published on: November 22, 2019
04:37Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis
Published on: April 25, 2025
Related Concept Videos
Acute Kidney Injury II: Pathophysiology
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Acute Pyelonephritis I: Introduction
Acute Pyelonephritis II: Diagnostic Studies and Management
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Kidney Transplant II: Surgical Procedure