Related Experiment Video
Updated: Jul 3, 2026

Isolation of Small Preantral Follicles from the Bovine Ovary Using a Combination of Fragmentation, Homogenization, and Serial Filtration
Published on: September 27, 2022
Ovarian antral follicle dynamics from birth through reproductive maturity: a mini-review
Hannah Lamar1, Rodolfo Cardoso2, Heidi Vanden Brink1
1Department of Nutrition, Texas A&M University, College, Station, TX, United States.
Abstract:
The transition from quiescence to a mature hypothalamic-pituitary-ovary (HPO) axis is a complex window of female reproductive maturation spanning puberty and the early postmenarcheal years. In reproductive maturity, the ovaries integrate reproductive and metabolic endocrine signals to coordinate both ovulatory and anovulatory waves of antral follicle development. Reproductive development towards a mature reproductive axis during adolescence is essential for optimal physiology and long-term reproductive health. However, abnormal reproductive maturation during this window is increasingly prevalent, highlighting the need to better understand the physiological and pathophysiological phases of reproductive maturity leading to ovarian antral follicle wave dynamics that define optimal reproductive maturity. In this mini-review, we will summarize literature in both humans and ruminant animal models to describe what is known - and unknown - of the endocrinology and morphology of follicle wave dynamics and follicular growth profiles from birth through reproductive maturity.
More Related Videos
06:40Collection of Human Follicular Fluid, Follicle Somatic Cells, and Immature Oocytes from Individuals Undergoing In Vitro Fertilization
Published on: October 24, 2025
12:36Whole Ovary Immunofluorescence, Clearing, and Multiphoton Microscopy for Quantitative 3D Analysis of the Developing Ovarian Reserve in Mouse
Published on: September 3, 2021
Related Concept Videos
Folliculogenesis
Hormonal Control of the Ovarian Cycle
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
Ovarian Cycle
Oogenesis
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is known...
Oogenesis
Ovaries
On the ovarian surface, a layer of cuboidal...