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Updated: Jul 3, 2026

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Clinical Application of Microscope-Assisted Minimally Invasive Anterior Lumbar Interbody Fusion
Published on: June 16, 2023
Managing lumbar adjacent segment disease: A description of minimally invasive techniques and algorithm
Arvind G Kulkarni1, Deepika H Jain2, Meet Kirit Shah2
1Mumbai Spine Scoliosis and Disc Replacement Centre, Mumbai, Maharashtra, India.
Journal of Craniovertebral Junction & Spine
|July 2, 2026
Summary
Minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) effectively manages lumbar adjacent segment disease (ASD) after prior spinal surgery. This algorithmic approach using posterior techniques significantly improves patient outcomes and reduces disability.
Area of Science:
- Spine Surgery
- Minimally Invasive Techniques
- Adjacent Segment Disease Management
Background:
- Adjacent segment disease (ASD) is a complication following spinal fusion.
- Effective management strategies for symptomatic lumbar ASD are crucial.
- Minimally invasive surgical techniques offer potential benefits for ASD treatment.
Purpose of the Study:
- To present a tailored, step-by-step guide for managing lumbar ASD using minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF).
- To outline four distinct surgical approaches for MIS-TLIF in patients with prior spinal fusion.
- To provide insights into an algorithmic approach for lumbar ASD management.
Main Methods:
- Retrospective study of 23 patients with lumbar ASD treated between January 2008 and December 2023.
- Application of four tailored MIS-TLIF techniques based on patient-specific factors.
- Evaluation of clinical outcomes using Oswestry Disability Index (ODI) and Visual Analog Scale (VAS).
Main Results:
- All 23 patients (age 40-80 years) showed significant clinical improvement without conversion to open surgery.
- Mean ODI decreased from 58.47 to 22.58.
- Mean VAS scores improved from 7.076 to 1.9.
Conclusions:
- The study demonstrates the efficacy of an algorithmic, posterior MIS-TLIF approach for lumbar ASD.
- Minimally invasive techniques provide significant clinical benefits for patients with adjacent segment disease.
- This approach offers valuable insights for surgeons managing complex spinal conditions.
Keywords:
Adjacent segment disease (ASD)degenerative spineminimally invasive surgeryspinal fusiontubular decompression
