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A hybrid approach for diabetic retinopathy stages classification using spatial and textural features
Mohsan Naqi1, Muhammad Arfan Jaffar1,2, Rab Nawaz Bashir3,4
1Faculty of Computer Science and Information Technology, The Superior University, Lahore, Pakistan.
Health Informatics Journal
|July 2, 2026
Summary
Diabetic Retinopathy (DR) detection is improved with machine learning models. The Random Forest model achieved 98% accuracy using hybrid features, offering an efficient solution for monitoring DR progression.
Area of Science:
- Ophthalmology and Medical Imaging
- Artificial Intelligence in Healthcare
- Diabetic Retinopathy Diagnosis
Background:
- Diabetic Retinopathy (DR) is a complication of diabetes damaging retinal blood vessels.
- Current DR detection methods are computationally intensive and lack accuracy.
- Automated, efficient DR monitoring is crucial for diabetic patients.
Purpose of the Study:
- To develop and evaluate computationally efficient machine learning models for multi-class DR classification.
- To compare the performance of various models including Random Forest, Logistic Regression, and deep learning architectures.
- To assess the utility of spatial, textural, and hybrid features for DR stage identification.
Main Methods:
- Extracted spatial features using Convolutional Neural Networks (CNN) and textural features using Grey Level Co-occurrence Matrix (GLCM).
- Developed hybrid features by combining spatial and textural information.
- Trained and evaluated Random Forest (RF), Logistic Regression (LR), Decision Tree (DT), Gaussian Naive Bayes (GNB), CNN, EfficientNet, PyramidCNN, and Pyramid Vision Transformer (PVT) models.
Main Results:
- The RF model with hybrid features achieved the highest accuracy (98.00%), outperforming existing methods by 1%.
- EfficientNet demonstrated competitive performance with 97.00% accuracy.
- Machine learning models showed computational efficiency in training and inference times.
Conclusions:
- The proposed RF model with hybrid features offers a highly accurate and efficient approach for DR classification.
- Machine learning models are suitable for deployment in low-resource clinical settings for automated DR monitoring.
- This study highlights the potential of AI in improving diabetic eye care and disease management.