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Related Concept Videos

Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
Mitral Stenosis IV: Nursing Management01:27

Mitral Stenosis IV: Nursing Management

A comprehensive nursing assessment is essential for patients with valvular heart disease, which involves any dysfunction of the heart valves that could impact blood flow and overall heart function.Subjective Data Collection:Chief Complaint and Present Illness: Start with the patient's primary concerns, focusing on the onset, duration, and progression of cardiac symptoms such as dyspnea, fatigue, chest pain, and palpitations.Past Medical History: Collect detailed information on any previous...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...

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Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

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Same author

Prognostic impact of <sup>18</sup>F-fluorodeoxyglucose positron emission tomography and cardiac magnetic resonance-proven cardiac involvement in pulmonary sarcoidosis: a single centre long-term cohort study.

BMC pulmonary medicine·2026
Same author

Association of Lipid Core Burden Index With Early Progression of Cardiac Allograft Vasculopathy in Patients After Heart Transplantation.

Circulation journal : official journal of the Japanese Circulation Society·2026
Same author

Effects of gadolinium-based contrast agents on the cardiac diffusion-weighted images of phantoms and patients.

Magma (New York, N.Y.)·2026
Same author

Modular driveline cable exchange due to internal cable damage in a patient with HeartMate 3: a case report.

European heart journal. Case reports·2026
Same author

Prognostic value of preprocedural pulmonary artery to ascending aorta ratio on non-contrast computed tomography in patients undergoing mitral transcatheter edge-to-edge repair.

Heart and vessels·2026
Same author

Prognostic value of <sup>18</sup>F-fluorodeoxyglucose positron emission tomography one month after initiation of prednisolone therapy in patients with cardiac sarcoidosis.

International journal of cardiology·2026

Related Experiment Video

Updated: Jul 3, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
05:25

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft

Published on: September 15, 2023

Adjunctive Cilostazol Therapy for Sinus Node Dysfunction After Heart Transplantation.

Kento Tamano1, Sakae Takenaka1, Toshiyuki Nagai1

  • 1Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

JACC. Case Reports
|July 2, 2026
PubMed
Summary

Cilostazol, a phosphodiesterase-3 inhibitor, may help manage severe sinus node dysfunction (SND) in heart transplant patients. This case study shows it improved heart rate and function without adverse events, potentially avoiding pacemaker implantation.

Area of Science:

  • Cardiology
  • Pharmacology

Background:

  • Sinus node dysfunction (SND) management after heart transplantation (HTx) is not well-established.
  • Phosphodiesterase-3 inhibitors like cilostazol have not been evaluated for this indication.
Keywords:
atrioventricular junctional rhythmcilostazolheart transplantationsinus node dysfunction

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Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
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