Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Neural Circuits

Neural Circuits

Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...

Auditory Pathway

Auditory Pathway

Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...

Motor and Sensory Areas of the Cortex

Motor and Sensory Areas of the Cortex

The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.

Diencephalon: Thalamus and Information Relay

Diencephalon: Thalamus and Information Relay

The thalamus, often called “the gateway to the cerebral cortex,” is vital in processing and directing sensory and motor signals throughout the brain. Almost all inputs destined for the cerebral cortex, except for olfactory signals, are relayed through the thalamus. The thalamus is a sophisticated relay station, channeling information from various brain regions to the cerebral cortex, as well as a filter, prioritizing certain signals over others based on current physiological states or needs.

Overview of Somatic Sensory Pathways

Overview of Somatic Sensory Pathways

Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Molecular and functional dissection using CaMPARI-seq reveals the neuronal organization for dissociating optic flow-dependent behaviors.

Nature communications·2026

Same author

Intrinsically accelerated cellular degradation is amplified by TDP-43 loss in ALS-vulnerable motor neurons in a zebrafish model.

Nature communications·2025

Same author

Inhibition mediated by group III metabotropic glutamate receptors regulates habenula activity and defensive behaviors.

Nature communications·2025

Same author

Calcium dynamics in habenular astrocytes regulate active coping within behavioral transitions.

Communications biology·2025

Same author

Maternal thyroid hormone is required to develop the hindbrain vasculature in zebrafish.

Communications biology·2025

Same author

Serotonin release in the habenula during emotional contagion promotes resilience.

Science (New York, N.Y.)·2024

Search research articles

Related Experiment Video

Updated: Jul 4, 2026

Eye Removal in Living Zebrafish Larvae to Examine Innervation-dependent Growth and Development of the Visual System

Eye Removal in Living Zebrafish Larvae to Examine Innervation-dependent Growth and Development of the Visual System

Published on: February 11, 2022

Hierarchical sensory processing in zebrafish thalamocortical-like circuits.

Anh-Tuan Trinh¹, Anna Maria Ostenrath¹, Ignacio Del Castillo-Berges¹

¹Kavli Institute for Systems Neuroscience and Centre for Algorithms in the Cortex, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.

Science (New York, N.Y.)

|July 2, 2026

Summary

The zebrafish preglomerular complex (PG) processes visual and vibrational information for the pallium. Hierarchical processing in this thalamocortical-like pathway reveals conserved sensory computation principles across vertebrates.

More Related Videos

Optogenetic Activation of Zebrafish Somatosensory Neurons using ChEF-tdTomato

Optogenetic Activation of Zebrafish Somatosensory Neurons using ChEF-tdTomato

Published on: January 31, 2013

Zebrafish In Situ Spinal Cord Preparation for Electrophysiological Recordings from Spinal Sensory and Motor Neurons

Zebrafish In Situ Spinal Cord Preparation for Electrophysiological Recordings from Spinal Sensory and Motor Neurons

Published on: April 18, 2017

Related Experiment Videos

Last Updated: Jul 4, 2026

Eye Removal in Living Zebrafish Larvae to Examine Innervation-dependent Growth and Development of the Visual System

Eye Removal in Living Zebrafish Larvae to Examine Innervation-dependent Growth and Development of the Visual System

Published on: February 11, 2022

Optogenetic Activation of Zebrafish Somatosensory Neurons using ChEF-tdTomato

Optogenetic Activation of Zebrafish Somatosensory Neurons using ChEF-tdTomato

Published on: January 31, 2013

Zebrafish In Situ Spinal Cord Preparation for Electrophysiological Recordings from Spinal Sensory and Motor Neurons

Zebrafish In Situ Spinal Cord Preparation for Electrophysiological Recordings from Spinal Sensory and Motor Neurons

Published on: April 18, 2017

Area of Science:

Neuroscience
Comparative Biology
Sensory Systems

Background:

Thalamocortical projections are crucial for cortical function in mammals.
Thalamocortical computations in non-mammalian vertebrates are poorly understood.

Purpose of the Study:

Investigate sensory processing in the zebrafish pallium, a cortical homolog.
Compare zebrafish thalamocortical-like circuits to those in other vertebrates.

Main Methods:

Electrophysiological recordings in zebrafish.
Analysis of sensory responses in the preglomerular complex (PG) and pallium.
Mapping of topographic organization and response properties.

Main Results:

The preglomerular complex (PG) is the main source of visual and vibrational input to the pallium.
PG and pallial projections show sensory-specific, topographically organized responses.
Pallial neurons exhibit hierarchical processing, from sensory-specific to multimodal and coincidence detection.

Conclusions:

The zebrafish pallium utilizes a thalamocortical-like pathway (PG) for sensory processing.
Hierarchical sensory transformations in topographically organized circuits represent a conserved principle across vertebrates.