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Pediatric Inpatient Influenza Vaccination Before, During, and After the COVID-19 Pandemic

Suchitra Rao1, Ravi Jhaveri2,3, Angela Dunn4

  • 1Department of Pediatrics (Infectious Diseases/Hospital Medicine/Epidemiology), University of Colorado Denver- Anschutz Medical Campus and Children's Hospital Colorado, Aurora, CO, United States.

Journal of the Pediatric Infectious Diseases Society
|July 2, 2026
PubMed

Insights

Influenza vaccination rates declined in hospitalized children during the COVID-19 pandemic and post-pandemic periods across multiple sites. Targeted strategies are needed to improve influenza vaccine uptake in this vulnerable pediatric population.

Area of Science:

  • Pediatric Infectious Diseases
  • Vaccinology
  • Public Health

Background:

  • Influenza vaccination is crucial for preventing severe illness in children.
  • Hospitalized children represent a high-risk group for influenza complications.
  • Understanding vaccination trends in hospitalized children is essential for public health planning.

Purpose of the Study:

  • To evaluate trends in influenza vaccination coverage among hospitalized children.
  • To assess the impact of the pandemic on influenza vaccine administration in pediatric hospital settings.
  • To identify the need for improved vaccination strategies in this population.

Main Methods:

  • Multi-site retrospective study design.
  • Analysis of influenza vaccination data from hospitalized children.
  • Evaluation of vaccination rates across the 2018-19 to 2023-24 influenza seasons.

Main Results:

  • Influenza vaccine administration showed a decrease during the pandemic and post-pandemic periods.
  • Vaccination screening protocols varied significantly among participating hospital sites.
  • A consistent decline in vaccine uptake was observed across all sites during the specified periods.

Conclusions:

  • Hospitalized children experienced reduced influenza vaccination rates during and after the pandemic.
  • The variability in screening highlights potential barriers to consistent vaccine administration.
  • Developing and implementing targeted interventions is necessary to enhance influenza vaccination coverage in hospitalized children.

Keywords:
hospital-based vaccination programinfluenza vaccinationinpatient vaccinationvaccination programvaccine delivery

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