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Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
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Cost-Effectiveness of Intracranial Aneurysm Screening: A Systematic Review
Andrei Schildt1, Ilari Rautalin1, Ville Vasankari1
1From the Department of Neurosurgery, Helsinki University Hospital and University of Helsinki, Finland.
Neurology
|July 2, 2026
Summary
Screening for unruptured intracranial aneurysms (UIAs) appears cost-effective for high-risk individuals but not the general population. Further research is needed due to limitations in current economic modeling studies.
Area of Science:
- Neurosurgery
- Health Economics
- Preventive Medicine
Background:
- Subarachnoid hemorrhage (SAH) presents significant mortality, morbidity, and economic burden.
- Screening for unruptured intracranial aneurysms (UIAs) may mitigate SAH-related outcomes.
- The cost-effectiveness of UIA screening remains unclear, particularly across different populations.
Conclusions:
- UIA screening appears cost-effective for high-risk populations.
- Evidence for general population screening is conflicting and based on low-quality modeling studies.
- Caution is advised; future research should focus on prospective data and clearly defined SAH risk stratification.
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