Related Experiment Video
Updated: Jul 4, 2026

Randomized Controlled Trial to Study the Acute Effects of Strength Exercise on Insulin Sensitivity in Obese Adults
Published on: December 1, 2023
Association between grip strength and the diabetes complications severity index (DCSI) in patients with type 2
Hideyuki Iwamoto1, Yuichiro Iwamoto1, Tomohiko Kimura1
1Department of Diabetes, Endocrinology, and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
Aims:
This study aimed to clarify the association between grip strength and the Diabetes Complications Severity Index (DCSI) in patients with type 2 diabetes mellitus (T2DM). While grip strength is widely used as an indicator of sarcopenia, its capacity to reflect the accumulation of diabetic complications has not been sufficiently investigated. In this study, we examined the relationship between grip strength and DCSI.
Methods:
The study included 501 T2DM patients hospitalized for diabetes education between 2018 and 2024. Grip strength was categorized into sex-specific quartiles. Severity was assessed using the DCSI. Kruskal-Wallis tests with Dunn's post hoc tests were used for interquartile comparisons, with further stratified analyses by age, sex, BMI, and presence of sarcopenia. Additionally, to examine the independent relationship of grip strength, a multiple regression analysis was conducted.
Results:
Lower grip strength was associated with higher DCSI scores. This trend persisted in stratified analyses by age, sex, BMI, and presence of sarcopenia. In the multiple regression analysis, grip strength was an independent negative predictor of DCSI scores.
Conclusions:
Reduced grip strength is independently associated with higher DCSI scores and may serve as a simple indicator suggesting an increased risk of complications.
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
Diabetes: Symptoms, Diagnosis, and Complications
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis
Type I Diabetes III: Clinical Manifestations
Type II Diabetes II: Pathophysiology
Type I Diabetes II: Pathophysiology