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Long-term lessons from MATCH01 macrophage therapy in cirrhosis
Bi-Sen Ding1, Biao Yang1, Zhongwei Cao1
1State Key Laboratory of Respiratory Health and Multimorbidity, Division of Abdominal Tumor Multimodality Treatment, Center of Infectious Diseases, West China Second Hospital, West China School of Basic Medical Sciences & Forensic Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
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In a long-term follow-up of a phase 1/2 clinical trial, Stuart Forbes and colleagues demonstrate that autologous macrophage therapy improves transplantation-free survival in patients with liver cirrhosis. These findings show the translational value of autologous macrophage-based regenerative therapy for advanced liver diseases.
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