Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nitroimidazole - albendazole combination therapy, quinacrine use, and risk factors in nitroimidazole-refractory giardiasis: a prospective multicentre observational study.

BMC infectious diseases·2026
Same author

A novel JAK1 variant in chronic eosinophilic leukaemia with response to benralizumab.

British journal of haematology·2026
Same author

Circulating eosinophils in patients with hypereosinophilic syndrome have heterogeneous immunophenotypes.

The journal of allergy and clinical immunology. Global·2026
Same author

Author Correction: Benralizumab versus placebo for hypereosinophilic syndrome: a randomized, placebo-controlled phase 3 trial.

Nature medicine·2026
Same author

Konzo: a nutrition-related tropical spastic paraparesis.

BMJ case reports·2026
Same author

Benralizumab versus placebo for hypereosinophilic syndrome: a randomized, placebo-controlled phase 3 trial.

Nature medicine·2026

Related Experiment Video

Updated: Jul 4, 2026

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
10:57

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Published on: August 22, 2012

Expert consensus on case definitions in human loiasis: a Delphi study.

Luzia Veletzky1, Spinello Antinori2, Sabine Bélard3

  • 1Department of Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria.

The Lancet. Infectious Diseases
|July 2, 2026
PubMed
Summary
This summary is machine-generated.

Experts reached consensus on standardized definitions for loiasis (Loa loa infection). These definitions will improve diagnosis, clinical management, and research communication for this filarial parasite infection.

More Related Videos

A Strategy for the Study of IL-9-Producing Lymphoid Cells in the Nippostrongylus brasiliensis Infection Model
08:38

A Strategy for the Study of IL-9-Producing Lymphoid Cells in the Nippostrongylus brasiliensis Infection Model

Published on: March 3, 2023

Related Experiment Videos

Last Updated: Jul 4, 2026

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
10:57

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Published on: August 22, 2012

A Strategy for the Study of IL-9-Producing Lymphoid Cells in the Nippostrongylus brasiliensis Infection Model
08:38

A Strategy for the Study of IL-9-Producing Lymphoid Cells in the Nippostrongylus brasiliensis Infection Model

Published on: March 3, 2023

Area of Science:

  • Medical Parasitology
  • Tropical Medicine
  • Public Health

Background:

  • Loiasis, caused by the filarial parasite Loa loa, requires standardized case definitions for effective clinical management and research.
  • Current definitions for loiasis manifestations like eyeworm and Calabar swelling lack harmonization, hindering scientific communication and guideline development.

Purpose of the Study:

  • To achieve expert consensus on case definitions and clinical aspects of loiasis.
  • To support the development of diagnostic and clinical management guidelines for loiasis.
  • To establish harmonized definitions for loiasis research and scientific communication.

Main Methods:

  • The Delphi method was employed, involving a panel of 18 experts in loiasis.
  • Statements on loiasis definitions and classifications were anonymously circulated and refined over four rounds.
  • Consensus was defined by specific agreement percentages and interquartile ranges (IQRs).

Main Results:

  • Consensus was achieved on proposed definitions for loiasis, with 83.3-100% agreement and IQR ≤ 1.
  • The term "occult loiasis" was agreed to be avoided due to its ambiguity.
  • The developed definitions are potentially applicable in both endemic and non-endemic settings.

Conclusions:

  • Consensus definitions for loiasis have been established, facilitating improved diagnosis and clinical care.
  • These harmonized definitions will enhance the quality and consistency of loiasis research.
  • The findings support the development of global guidelines for managing loiasis and related filarial infections.