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Clinical Applications of Pure Recombinant Human Platelet-Derived Growth Factor BB in Esthetic Medicine and Plastic
Samuel E Lynch1, Christopher K Hee1, Rod Rohrich2
1Lynch Regenerative Medicine, LLC, Franklin, TN, USA.
Abstract:
Goals in plastic surgery and aesthetic medicine include minimizing healing complications, optimize aesthetic outcomes and improve patient satisfaction. Platelet-derived growth factor BB (PDGF-BB) is among the most potent natural activators of healing. A pharmaceutical copy of natural PDGF-BB, (rhPDGF-BB or pure PDGF) is the active ingredient in four US Food and Drug Administration-approved therapies to stimulate healing of skin, mucosa, gingivae or bone. Here we describe the mechanism of action and clinical uses of off-the-shelf pure PDGF in plastic surgery and aesthetic medicine as a post-treatment adjunct to enhance patient satisfaction.