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Published on: June 16, 2022
[Recognition and treatment of coronary microcirculation dysfunction with TCM]
Yu Lan1, Xiao-Ya Wang1, Zhe-Yuan Liang1
1Guang'anmen Hospital, China Academy of Chinese Medical Sciences Beijing 100053, China.
Summary
Traditional Chinese Medicine (TCM) offers a holistic approach to treating coronary microcirculation dysfunction, addressing key pathological mechanisms to improve patient outcomes and quality of life.
Area of Science:
- Cardiology
- Integrative Medicine
- Traditional Chinese Medicine
Background:
- Coronary microcirculation dysfunction involves structural/functional changes in small vessels, impacting myocardial perfusion.
- Current treatments face challenges like low drug efficacy and adverse reactions.
- TCM categorizes this condition as "chest Bi syndrome" or "heart pain," with etiologies including pathogenic factors and lifestyle.
- Core TCM pathogenesis involves Qi stagnation, blood stasis, and phlegm turbidity.
Purpose of the Study:
- To explore the TCM perspective on coronary microcirculation dysfunction.
- To elucidate TCM's multi-target therapeutic strategies and efficacy.
- To outline TCM treatment principles and formula selection for specific syndromes.
Main Methods:
- Review of TCM theory regarding coronary microcirculation dysfunction.
- Analysis of TCM etiological factors and pathogenic mechanisms.
- Identification of key TCM formulas and treatment principles based on syndrome differentiation.
Main Results:
- TCM addresses coronary microcirculation dysfunction through holistic regulation, targeting neuroendocrine, vascular endothelial, inflammatory, oxidative stress, and metabolic pathways.
- TCM interventions aim to alleviate angina, delay progression, improve prognosis, and enhance quality of life.
- Specific TCM formulas are recommended for Qi stagnation (Chaihu Longgu Muli Decoction), blood stasis (Guizhi Fuling Pills, Xuefu Zhuyu Decoction), and phlegm turbidity (Gualou Xiebai Banxia Decoction, Wendan Decoction).
Conclusions:
- TCM provides a comprehensive therapeutic strategy for coronary microcirculation dysfunction by addressing its underlying mechanisms.
- Adherence to TCM principles, including syndrome differentiation and formula selection, is crucial for optimizing treatment efficacy.
- TCM offers a valuable complementary approach to conventional medicine for managing this complex cardiovascular condition.
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