Related Experiment Video
Updated: Jul 4, 2026
A Mouse Model of Ankle-Subtalar Complex Joint Instability
Published on: October 28, 2022
MRI-based Predictors and Risk Constellations of Chronic Ankle Instability After Acute Lateral Ankle Sprain: A
Ruihong Chen1, Haoxue Bai1, Xiaoyi Wang1
1Clinical AI Imaging Research Center, Department of Medical Imaging, Shanxi Medical University, Taiyuan, Shanxi Province, PR China (R.C., H.B., X.W., Y.W., Y.X., L.G., Q.Z., Y.Z.); Department of Radiology, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi Province 030001, PR China (R.C., H.B., X.W., Y.W., X.S., S.C., Y.X., L.G., Q.Z., Y.Z., J.N.).
Magnetic resonance imaging (MRI) can identify predictors of chronic ankle instability (CAI) after acute lateral ankle sprain (LAS). Talar osteochondral lesions and talonavicular ligament injuries, combined with other factors, significantly increase CAI risk.
Area of Science:
- Orthopedics
- Radiology
- Sports Medicine
Background:
- Chronic ankle instability (CAI) frequently follows acute lateral ankle sprain (LAS) but early identification of at-risk individuals is difficult.
- Magnetic resonance imaging (MRI) is crucial for evaluating soft tissue and bone injuries after LAS.
- Understanding MRI predictors can improve patient stratification and management following LAS.
Purpose of the Study:
- To identify independent MRI predictors of CAI after an initial LAS.
- To explore clinically relevant risk constellations associated with CAI development.
- To develop prediction models incorporating these risk factors for improved patient assessment.
Main Methods:
- A multicenter retrospective study of 474 patients with acute LAS who underwent ankle MRI within two weeks.
- Patients were assessed for CAI at 24-month follow-up using validated clinical tools.
- Two musculoskeletal radiologists blinded to outcomes evaluated MRI scans for ligament injuries, bone edema, effusion, and osteochondral lesions.
Main Results:
- CAI developed in 34.4% of patients.
- Independent MRI predictors of CAI included age, talar osteochondral lesions (TOL), and talonavicular ligament (TNL) injury.
- Specific risk constellations (e.g., TOL with male sex, severe TNL injury with other ligament injuries) significantly elevated CAI risk.
Conclusions:
- Talar osteochondral lesions and talonavicular ligament injuries detected by MRI are significant independent predictors of CAI post-LAS.
- Identified risk constellations improve the prediction of CAI development.
- These findings can aid in the early identification of high-risk patients for targeted interventions.
More Related Videos
07:52Evaluating Postural Control and Lower-extremity Muscle Activation in Individuals with Chronic Ankle Instability
Published on: September 18, 2020
07:24Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus
Published on: January 23, 2018