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Updated: Jul 4, 2026

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
Published on: October 18, 2024
Are diabetologists against metabolic surgery?
Anne-Cécile Paepegaey1,2, Anne-Laure Proust3, Virginie Pichot-Delahaye4
1Department of Endocrinology, Médipôle Hôpital Mutualiste, 158 rue Léon Blum, Villeurbanne, 69100 France.
Introduction:
Since 2022, the French Haute Autorité de Santé (HAS) has allowed metabolic surgery for patients with uncontrolled type 2 diabetes and a body mass index (BMI) between 30 and 34.9 kg/m². The main objective of this study was to identify the characteristics of patients to whom diabetologists propose metabolic surgery.
Materials And Methods:
This was a single-center, prospective study including patients with diabetes and a BMI between 30 and 34.9 kg/m², conducted between January 2024 and March 2025. A questionnaire was completed by diabetologists, including information on diabetes, comorbidities, and a physician-rated adherence out of 10. The physician then indicated whether metabolic surgery was proposed to the patient.
Results:
Data from 72 patients were collected. Twenty-six (36.1%) were women; the mean age was 50.0 years and the mean BMI was 32.2 kg/m². The mean duration of diabetes was 6.9 years and the mean HbA1c was 7.7%. The mean number of antidiabetic treatments was 2.8, and 49/72 (68.1%) patients were treated with insulin. Metabolic surgery was proposed to 25 patients (34.7%). Surgery was considered for patients with higher HbA1c (8.6 vs. 7.2%, p < 1 × 10⁻⁴), a longer duration of diabetes (9.0 vs. 5.8 years, p = 0.02), more antidiabetic treatments (3.6 vs. 2.4, p < 1 × 10⁻⁴), and more often for patients receiving insulin (96.0% vs. 53.2%, p < 1 × 10⁻⁴). There was no significant difference in age, BMI, sex, or physician-rated adherence score between patients to whom surgery was proposed and those to whom it was not.
Conclusion:
Metabolic surgery was preferentially proposed to patients with more advanced diabetes, in accordance with current recommendations. However, patient acceptance remained very low, highlighting a major barrier to implementation.
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