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Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
Published on: October 18, 2024
Are diabetologists against metabolic surgery?
Anne-Cécile Paepegaey1,2, Anne-Laure Proust3, Virginie Pichot-Delahaye4
1Department of Endocrinology, Médipôle Hôpital Mutualiste, 158 rue Léon Blum, Villeurbanne, 69100 France.
Journal of Diabetes and Metabolic Disorders
|July 3, 2026
Summary
Metabolic surgery is proposed for patients with advanced type 2 diabetes and obesity (BMI 30-34.9 kg/m²). However, patient acceptance remains low, indicating implementation barriers for this diabetes treatment.
Area of Science:
- Endocrinology
- Bariatric Surgery
- Diabetes Management
Background:
- French guidelines (since 2022) permit metabolic surgery for type 2 diabetes patients with BMI 30-34.9 kg/m².
- Identifying patient profiles for surgical consideration is crucial for effective treatment allocation.
Purpose of the Study:
- To determine the characteristics of patients with type 2 diabetes and obesity (BMI 30-34.9 kg/m²) for whom diabetologists propose metabolic surgery.
Main Methods:
- Prospective, single-center study (Jan 2024-Mar 2025).
- Diabetologist questionnaires collected data on diabetes, comorbidities, and adherence.
- Physicians indicated if metabolic surgery was proposed.
Main Results:
- Metabolic surgery was proposed to 34.7% of 72 patients (mean age 50, mean BMI 32.2 kg/m²).
- Proposed surgery correlated with higher HbA1c, longer diabetes duration, more antidiabetic treatments, and insulin use.
- No significant differences in age, BMI, sex, or adherence were found between proposed and non-proposed groups.
Conclusions:
- Metabolic surgery is preferentially offered to patients with more advanced diabetes, aligning with recommendations.
- Low patient acceptance presents a significant barrier to the implementation of metabolic surgery for this patient group.
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